Research

The power of the Internet over depression
To fight depression among homebound adults, Social Work Professor Namkee Choi uses the video chat tool Skype and connects patients with therapists.
Witnesses to civil rights-era life
Explore the Briscoe Center's R.C. Hickman and Calvin Littlejohn photo collections that chronicle Texas' dynamic African American communities.
Labor or leisure?
A new economics study by Professor Daniel Hamermesh lends insight into how people spend their free time when their work weeks are shorter.
The high value of short-lived worms
Researchers have devised a simple test using dopamine-deficient worms for identifying drugs that may help people with Parkinson's disease.
Meet a Game Changer: Lauren Ancel Meyers
In this video, the mathematical epidemiologist reveals why she's so passionate about studying the spread and control of infectious diseases.
Know - Your connection to a world of ideas
To fight depression among homebound adults, Social Work Professor Namkee Choi uses the video chat tool Skype and connects patients with therapists.
Explore the Briscoe Center's R.C. Hickman and Calvin Littlejohn photo collections that chronicle Texas' dynamic African American communities.
A new economics study by Professor Daniel Hamermesh lends insight into how people spend their free time when their work weeks are shorter.
Researchers have devised a simple test using dopamine-deficient worms for identifying drugs that may help people with Parkinson's disease.
In this video, the mathematical epidemiologist reveals why she's so passionate about studying the spread and control of infectious diseases.

Recovery Act

The University of Texas at Austin has received more than $117 million for research through the American Recovery and Reinvestment Act of 2009. Research investment includes major pieces of instrumentation, investigations in health, energy, infrastructure and other areas, and expanding supercomputing capabilties.

Read more about the university's research through federal economic Recovery Act funds.

Research Alerts

Get the latest news on research grant opportunities, awards winners and newsmakers in the Research Alert.

Further Findings

Use of methamphetamines is on the rise nationally after a decrease a few years ago, according to university researchers.

Use of meth dropped significantly in 2007 and 2008 after laws limiting the availability of pseudoephedrine went into effect made it much harder to obtain key ingredients.


Jane Maxwell, a senior research scientist in the School of Social...

Researchers from the undergraduate level to the Nobel Prize explore, discover and innovate in the arts, humanities and sciences and across disciplinary boundaries. The impact of the university's research ripples through Texas and around the world.

Research Facts

Todd Ditmire and the Petawatt Laser$642 million was awarded in sponsored research in 2009-2010.

$14.3 million in revenue was received from the licensing of university technology.

The university runs one of the world's fastest supercomputers and one of the most powerful lasers.

Texas researchers were quickly on-site after the Haiti earthquake and Deepwater Horizon oil spill.

About 800 patents have been awarded to the university.

The university's 17 libraries hold more than nine million volumes.

The Harry Ransom Center displays a Gutenberg bible and the world's first photo.

Quetzalcoatlus, the largest flying creature ever discovered, was found by a university student. A replica is on display at the Texas Memorial Museum.

Research News

Published: Feb. 1

A new form of proteins discovered by researchers at The University of Texas at Austin could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics: delivering drugs to patients safely, easily and more effectively.

The protein formulation strategy, discovered by chemical engineering faculty members and students in the Cockrell School of Engineering, is unprecedented and offers a new and universal approach to drug delivery — one that could revolutionize treatment of cancer, arthritis and infectious disease.


Chemical Engineering Professors Jennifer Maynard, Keith P. Johnston and Thomas Truskett have discovered a new form of proteins that could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics: delivering drugs to patients safely, easily and more effectively.

“We believe this discovery of a new highly concentrated form of proteins — clusters of individual protein molecules — is a disruptive innovation that could transform how we fight diseases,” said Keith P. Johnston, a chemical engineering professor and member of the National Academy of Engineering. “It required integration of challenging contributions in fundamental science and engineering from three of our chemical engineering research groups.”

The research, led by Johnston, Chemical Engineering Professor Thomas Truskett and Assistant Professor Jennifer Maynard, was published online recently ahead of a print version to appear soon in the ACS Nano journal.

“The real challenge in developing therapeutics is how do you deliver them to patients,” Maynard said.

Typically, protein biopharmaceuticals are administered intravenously at dilute concentrations in a hospital or clinic. Scientists and engineers have long tried to produce safe drugs at higher concentrations so that a patient could self-inject the drugs at home, similar to an insulin shot. But doing so has been stymied by the fact that proteins, in high-concentration formulations, form aggregates that could be dangerous to patients and gels that cannot be injected.

The Cockrell School research team has introduced a new physical form of proteins, whereby proteins are packed into highly concentrated, nanometer-sized clusters that can pass through a needle into a patient to treat disease. The novel composition avoids the pitfalls of previous attempts because drug proteins are clustered so densely that they don’t unfold or form dangerous aggregates.

“This general physical concept for forming highly concentrated, yet stable, protein dispersions is a major new direction in protein science,” Johnston said.

Through the research, the team formed protein nanoclusters in water simply by properly adjusting the pH (to lower protein charge) and adding sugar to crowd protein molecules together. Upon dilution, or subcutaneous injection into a mouse, the proteins separate back into individual stable molecules with biological activity. Once injected, the protein in the bloodstream attacks targeted cells and tumors similarly as for protein delivered via IV therapy.

Since the researchers began their collaboration in 2004, the nanoclusters they developed have been successfully tested on mice, multiple major pharmaceutical companies are pursuing them and three patents have been filed through the university’s Office of Technology Commercialization.

Two undergraduate students also played a key role in the research, Johnston said, leading many others to realize the benefit of undergraduate research projects.

“Numerous undergraduate students at UT are realizing the enormous opportunities they have to contribute to science, engineering and human health when they get involved in research projects,” Johnston said.

The research is funded by the National Science Foundation, the National Institutes of Health, the Welch Foundation and the Packard Foundation. Starting in 2012, two major pharmaceutical companies will fund the work.

Published: Jan. 30

In an age in which "multitasking" is often cited as a core competency for employees, organizational communication researchers at The University of Texas at Austin have begun to better understand the nuances of how different individuals accomplish multiple tasks.

Such nuances can be important to organizations wanting to hire the right individual for a job and for employees seeking the best organizational and cultural fit. For young people entering a difficult job market, it could provide guidance needed to pursue the right career.

The study, which appears in this month's issue of Human Communication Research, was conducted by Assistant Professor Keri Stephens and Associate Professor Dawna Ballard, both in the Department of Communication Studies, along with Assistant Professor Jaehee Cho from the University of North Carolina at Charlotte. The researchers established more nuanced terms —“sequential multitasking” and “simultaneous multitasking” — to more accurately reflect individuals’ and organizations’ practices.

The two-part study consisted of several focus groups composed of millennials (people born between 1980 and 1995) articulating the differences between three types of multiple-task completion preferences: simultaneous tasking, single tasking and sequential tasking. The subsequent experiment tested the effect that exposure to an organizational website depicting one of the three types of multiple-task completion preferences had on people's opinions of work practices in those organizations.

It found that millennials perceive work environments to be faster paced, with an increased workload, when those organizations expect multiple tasks to be completed at the same time — simultaneously as opposed to allowing work tasks to be completed sequentially or one at a time. These multitasking distinctions influence people’s perceptions of how much they will need to be available outside of work hours.

The research also found that female millennials had a more nuanced view than men in the same age group of how organizational multitasking cultures could influence the expectations for availability outside of work.

"Not all millennials want to work in a fast-paced organization that expects them to be available 24/7," said Stephens, who is the lead author of the study. "Many student millennials have privately confessed that they do not consider themselves simultaneous multitaskers, and they are worried when prospective employers make multitasking part of a job description."

This study provides evidence that sequential multitasking, juggling many projects in a sequence, is also considered multitasking, but it is perceived differently than the faster paced simultaneous type of multitasking. More research is needed to determine which type of multitasker is more productive over time.

Published: Jan. 27

The type of school a child attends may exacerbate the negative effect that family instability has on academic performance, according to a new study in the January issue of Sociology of Education.

Students who attend more rigorous, academically oriented schools are affected to a greater degree in their course-taking behaviors than students who attend schools with lower levels of "academic press," according to study co-author Shannon Cavanagh, a sociology professor at The University of Texas at Austin.

"We were curious about whether the family instability effect on course-taking behaviors might be different (stronger or weaker) in different kinds of schools," she said.

What Cavanagh and study co-author Paula Fomby, an assistant professor in sociology at the University of Colorado-Denver, found supports what is called the "mismatch hypothesis," which suggests that students who have experienced repeated changes in their family structure status will be less successful academically when attending schools with higher levels of academic press.

Cavanagh and Fomby used data from a national longitudinal study of students who were in high school in the mid-1990s. They chose to focus on math course-taking patterns, because math is one of the strongest predictors of college matriculation. Academic status in mathematics at the end of high school not only represents interest and ability in the subject, but, more generally, it captures a clearer picture of a student's cumulative high school career.

Because the data from the chosen study included information on students' school records and their families as well as characteristics of their schools, Cavanagh and Fomby were able to relate a specific characteristic of each student — their family structure history — with school characteristics.

"This interaction allowed us to determine the context in which a student's own family history had the greatest impact on their course-taking patterns," Cavanagh said.

The findings suggest that children in higher academic press schools tend to do better than those in lower performing schools. Experiences of family instability, however, chip away at this advantage more in high press schools than in low press schools. All else equal, students who attended schools with higher levels of academic press were about 15 percent less likely to complete college-preparatory math when they had experienced three or more changes in family structure, compared with students who had experienced no family structure change prior to entering high school.

"While students in a high-academic press school, regardless of family instability histories, are higher achieving in terms of course-taking compared with their peers overall, students who have experienced repeated family structure changes lose some part of their advantage," Cavanagh said. As such, Cavanagh and Fomby frame their results in terms of "lost gains."

The results of the study could complicate the work of policymakers and educators who have historically sought to mitigate social disadvantages through access to opportunities and resources found in higher-performing schools. Cavanagh suggests the study highlights the need for teachers and school leaders to clarify what she calls the "opaque process of college preparation" and to help parents ask the right questions about their student’s college preparation.

"(School administrations) can remove some of this opacity with broad information campaigns about the expectations that colleges and employers have for student learning," Cavanagh suggested. "Local business and community leaders who join schools in an effort to prepare college-ready high school graduates may also be effective in reaching parents and adolescents."

Research Events

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